Do you want to know your ovarian age?                                                                                                                                                                           ————Anti-Mullerian hormone (AMH) will tell you       As time passes by, women start to show symptoms associated with aging, such as facial sagging, dull skin, forgetfulness, dreaminess, insomnia and irritability. All of these may be result from the fact that your ovaries are slowly aging. Ovarian reserve function is an important indicator of female reproductive ability, which refers to the potential of the ovaries to produce the number and quality of eggs, and indirectly reflects the function of the ovaries. As age increases, the number of follicles decreases accordingly. Studies have found that the follicle density of women over 35 years old significantly decreases, and women over 40 years old experience a sharp decline in follicle number. When the ovarian reserve is completely consumed, women enter menopause[1].     Clinical indicators such as hormone testing, ovarian dynamics testing, follicle-stimulating hormone, ovarian and antral follicle ultrasound testing are commonly used to evaluate ovarian reserve function. However, these indicators have requirements for testing time or operational experience. The detection of AMH can effectively solve these problems and become the most direct testing method of ovarian reserve function.     What is AMH?     AMH is a glycoprotein hormone structurally related to inhibin and activin from the transforming growth factor beta superfamily, whose key roles are in growth differentiation and folliculogenesis. AMH expression is critical to sex differentiation at a specific time during fetal development, and appears to be tightly regulated by nuclear receptor SF-1, transcription GATA factors, sex-reversal gene DAX1, and follicle-stimulating hormone (FSH)[2]. The more small antral follicles in the ovaries, the higher the concentration of AMH;likewise, as follicles are gradually consumed with age and various factors, AMH concentration will also decrease. By the time of the menopause, the concentration of AMH gradually decreases to zero. Therefore, examining AMH can effectively assess the "age" of the ovaries.         Applications of AMH     n AMH is a good indicator for evaluating ovarian reserve function and is ...

Tragic! A mother passed away from heat stroke as she selflessly gave the fan to her child on a hot summer day!According to a recent news report in Zhejiang, China, a woman in her thirties suffered from severe heat stroke. On a scorching day, she didn't turn on the air conditioner at home and gave the fan to her child. By the time her family realized she wasn’t well enough and took her to the hospital, she had already fallen into a deep coma. Despite of all doctors' efforts, nothing the doctors could do to help.     The weather is heating up, and as the temperature rises, so does the risk of heat stroke. We aren't talking about simply feeling hot, or uncomfortable, or sweating excessively. Heat stroke is life threatening emergency!   01. What is Heat Stroke?   Heat stroke, also known as severe heat exhaustion, is a life-threatening clinical syndrome caused by an imbalance between heat production and heat dissipation in the body due to exposure to a hot environment or intense physical activity. It is characterized by a core temperature higher than 40°C, along with symptoms such as burning sensation of skin, altered mental status (such as delirium, seizures, or coma), and multi-organ system injury.       Heat stroke can be divided into classic heat stroke (CHS) and exertional heat stroke(EHS).It is categorized as classic when it results from passive exposure to extreme environmental heat and as exertional when it develops during strenuous exercise. Exertional heatstroke affects predominantly young and healthy individuals.   02. Epidemiological Characteristics of Heat Stroke       Of all extreme weather conditions, heat is the most deadly. It kills more people in the U.S. in an average year than hurricanes, tornadoes and floods combined. According to data from abroad, the incidence of classic heat stroke during the summer heatwave is (17.6~26.5) per 100,000 population, with a hospital mortality rate of 14%~65% and an ICU patient mortality rate of >60%. Patients with exertional heat stroke accounted for 8.6%~18% of those with heat-related illnesses, and the mortality rate is >30% when combined with hypotension. Additionally, classic heat stroke has a higher mortality rate, which may be related to underlying pre-existing diseases.   03. Prevention Measures for Heat Stroke       04. Diagnostic Methods of Heat Stroke    Medical history information:   ① Exposure to high temperature and high humidity environment;② High-intensity exercise.   Clinical Features: ① Central nervous system dysfunction (such as coma, seizures, delirium, abnormal behavior, etc.);② Increased skin temperature or sustained sweating&nb...