Getein Coagulation Series: Fully Automated Testing for Coagulation Assays Getein Coagulation Solution     FIB (Fibrinogen) Reagent Kit (Clotting Method) TT (Thrombin Time) Reagent Kit (Clotting Method) PT (Prothrombin Time) Reagent Kit (Clotting Method) DD (D-Dimer) Reagent Kit (Immunoturbidimetric Method) AT III (Antithrombin III) Reagent Kit (Chromogenic Substrate Method) APTT (Activated Partial Thromboplastin Time) Reagent Kit (Clotting Method) FDP (Fibrin (ogen) Degradation Products) Reagent Kit (Immunoturbidimetric Method) Hemostasis and thrombosis testing is essential for perioperative bleeding, thrombosis, and anticoagulation management. Getein's 7-item coagulation reagents and a full range of consumables are available worldwide. With 200 T/H and 400 T/H fully automated coagulation analyzers. Two Models for Diverse Needs     Two Modular Systems for Scalable Performance    

Getein Animal Diagnostic Solutions for Veterinary Care Getein Animal   Getein Animal Diagnostic Solutions for Veterinary Care As veterinary medicine becomes more precise, testing efficiency, result reliability and ease of operation are becoming increasingly important in daily clinical practice. Getein Animal offers seven dedicated veterinary instruments across four major testing areas: clinical chemistry, molecular diagnostics, immunofluorescence and hematology. Together, they help veterinary professionals build a more efficient workflow from sample processing to report generation. Product Introduction     CM-50 Vet uses disc-based microfluidic technology to integrate multiple chemistry tests into a single reagent disc. · Results in 12 minutes · Micro-volume sampling with only 100 μL · Multiple test combinations from one sample · No pumps, tubing or cleaning fluids required The manual lists 10-item, 11-item, 18-item and 26-item panels, as well as free combination discs, for applications including liver and kidney evaluation, glucose, proteins, pancreatic function, cardiac markers and lipid metabolism.     GN 7000 Vet integrates nucleic acid extraction, PCR amplification, detection and result output into one automated workflow. · Sample in, result out · Fastest turnaround time of 35 minutes · Gravity-driven microfluidic technology · Multiple tests at once, maximizing workflow and save time The fully enclosed microfluidic chip design helps reduce contamination during operation, while QR-code recognition and multiple-test detection improve workflow efficiency.     A compact single-channel analyzer · Two modes & fast result ·  Android touchscreen operation · Optional lithium-ion battery · Barcode recognition, RFID card and Wi-Fi support     Designed for higher-throughput testing with four channels and an integrated temperature-control module. · Multi-channel, 4 incubation channels for saving operation time · Constant testing temperature of 32°C · Android touchscreen operation · RFID card and Wi-Fi support     A handheld immunofluorescence quantitative analyzer for mobile, point-of-care and flexible testing scenarios. · Single channel · Results in 3–15 minutes · Constant incubation temperature of 32°C · Built-in battery and temperature-control module · Continuous operation for approximately 8+ hours The three models support applications across inflammation, infectious diseases, pancreatic function, cardiovascular assessment and hormone testing.     3-Part Differential Automatic Hematology Analyzer · 19 reportable parameters + 3 histograms · Use double-channel test mode with 60 T/H · Whole-blood sample volume: 10 μL · Built-in printer with Wi-Fi data transmission · Supports cats, d...

One Drop of Fingertip Blood: Detect Hidden Nutritional Risks for Children When getting health check-ups for children, many parents face a difficult choice: venous blood draws can be dis-tressing for children and upsetting for their parents, while a basic complete blood count may not reveal early-stage iron deficiency or vitamin D deficiency. By the time frequent illnesses or slower-than-expected growth become apparent, valuable opportunities for early intervention may already have been missed. Getein Biotech can make children's health check-ups different. International Consensus Ferritin and 25-OH-VD are two core indicators in pediatric nutritional assessment: Ferritin, an essential indicator of iron stores, is recommended by the WHO and pediatric guidelines in many countries for the early screening of iron-deficiency anemia. 25-OH-VD, a widely recognized indicator for assessing vitamin D status, is broadly used in areas including childhood rickets, immune function, and growth and development. European countries and the United States have incorporated these two indicators into routine pediatric preventive care and rapid capillary-blood screening systems for high-risk populations, supporting microsample blood testing in primary care and emergency departments. Understanding the Numbers How should you interpret your child's "nutrition report card"? Many parents look completely puzzled when they receive the health-examination report: What exactly do these numbers mean? Ferritin (SF) Reference Standards According to the 2023 Expert Consensus on the Prevention and Treatment of Iron Deficiency and Iron-Deficiency Anemia in Children:     25-OH-VD Reference Standards According to the 2025 Consensus on the Clinical Use of Vitamin D and Its Analogs:     With a single test, you can clearly understand your child’s true nutritional reserves. A child being full does not mean the child is eating well; the data tell the real story. The "Pain" of Taking a Child for a Health Examination How many parents have experienced a scene like this? You take your child for a health examination. The nurse picks up a venous blood-draw needle, and before the needle is even inserted, the child is already crying inconsolably. The parent holds the child's arm still while the nurse repeatedly searches for a vein; if the first attempt fails, a second is needed. The child cries until drenched in sweat, while the parent's eyes redden with distress… Even when the blood draw goes smoothly, you still have to wait most of the day, or even several days, to receive the results. Getein Capillary Blood Screening One Drop of Fingertip Blood, Two Key Tests With a single capillary blood sample, two key tests can be completed simultaneously: 25-Hydroxyvitamin D (25-0H-VD) — assesses bone development and immune function Ferritin (Fer) — evaluates iron stores and provides early warning of iron-deficiency anemia Five Key Advantages of Getein Capillary-Bloo...

TB (Tuberculosis): Know It, Test It, Stop It TB (Tuberculosis) has followed humanity for centuries, often beginning quietly with symptoms that are easy to overlook. In 2024, an estimated 10.7 million people developed TB and 1.23 million died from the disease. Yet around 2.4 million people were either not diagnosed or not officially reported. Closing this gap begins with earlier, faster, and more accessible testing.     When Should We Think About TB? TB is caused by bacteria from the Mycobacterium tuberculosis complex, often reported as MTB. It most commonly affects the lungs, but it can also involve other parts of the body. Common warning signs include: •A cough that does not go away, sometimes with blood •Chest pain, fever, or night sweats •Unexplained tiredness, loss of appetite, or weight loss     These symptoms do not always mean TB, but they deserve medical attention - especially after close contact with someone who has TB or when the immune system is weakened. Why Diagnosis Used to Take So Long For pulmonary TB, sputum is the most common sample and collection is usually non-invasive. For decades, testing relied mainly on microscopy and culture: •Smear microscopy is fast and affordable, but it can miss cases when few bacteria are present and cannot reliably distinguish MTB from other mycobacteria. •Culture is highly reliable and remains important for further testing, but results may take several weeks.     Molecular testing changed the picture. Instead of waiting for bacteria to grow, it looks directly for MTB genetic material. Depending on the assay and testing workflow, results can be available within hours - giving clinicians useful information much sooner. Molecular POCT: Bringing Answers Closer Molecular point-of-care testing (POCT) brings advanced detection closer to the patient. Compact systems can support testing in clinics, community facilities, regional laboratories, and other decentralized settings. • Faster answers - from 30 minutes to 1 hour, depending on the assay and workflow. Getein's Akso MTB Real-time PCR Kit delivers results in just 37 minutes • Greater sensitivity than smear microscopy, helping detect more MTB-positive samples • Less reliance on long-distance sample transport and centralized infrastructure • Earlier information to support timely clinical decisions and follow-up Faster Detection. Wider Access. Better-Informed Care Getein offers two molecular POCT analyzers, GN 7000 Akso PCR System and GN 7120 Akso PCR System, designed for different testing throughput needs. With a streamlined "samples in, results out"workflow, both systems deliver MTB results in as little as 37 minutes, helping bring molecular testing closer to the point of care.   Both analyzers feature two reaction chambers. The GN 7000 provides four testing channels, while the GN 7120 provides 12, offering flexible capacity for different testing settings.     ...

The Echo of Tuberculosis in Your Immune System: Understanding TB-IGRA I. A Disease That Has Never Faded Tuberculosis (TB) is one of the world‘s oldest and most persistent infectious diseases, causing over 10 million new cases and 1.3 million deaths annually. It primarily affects the lungs but can spread via the bloodstream to bones, kidneys, the brain, and lymph nodes. The greatest challenge: Infection ≠ disease. About a quarter of the global population carries Mycobacterium tuberculosis without symptoms and without being contagious — a state known as latent TB infection (LTBI). However, when immunity wanes — due to aging, diabetes, HIV, or immunosuppressive therapy — the dormant bacteria may reactivate, causing active TB.     Thus, modern TB control is not just about finding active cases, but identifying who carries the bacteria and is at future risk. To do this, we need a tool that detects the immune system's memory of TB, not the bacterium itself. That tool is TB-IGRA. II. What Is TB-IGRA? TB-IGRA (Tuberculosis Interferon-Gamma Release Assay) is a blood test that does not look for the bacteria itself, but instead asks your immune system whether it has ever encountered TB. During the test, a blood sample is stimulated with TB-specific antigens. If T-cells recognize these antigens, they release interferon-gamma (IFN-γ), which is then quantitatively measured. A result above the threshold is positive; below is negative.     Its key advantage over traditional skin tests (TST) is that the antigens used are absent from BCG and most non-tuberculous mycobacteria (NTM), making TB-IGRA more specific and reliable. Additionally, it requires only a single blood draw with no need for a second visit, avoiding false positives caused by BCG vaccination.     III. Priority Groups for TB-IGRA Detection TB-IGRA is primarily recommended for the following high-risk groups: ①Close contacts of active TB patients (especially household contacts); ②Patients about to start immunosuppressive therapy (e.g., TNF inhibitors); ③Organ or stem cell transplant candidates; ④HIV-positive individuals; ⑤Immigrants from high TB burden countries. IV. Clinical Value of TB-IGRA Key clinical applications of TB-IGRA include the following: Aiding in the diagnosis of active TB: When a patient has symptoms or imaging findings suggestive of TB, but sputum smear is negative, a positive IGRA result can support clinical suspicion. Guiding preventive therapy decisions: A positive result indicates infection, but it cannot distinguish between latent and active TB. The decision to start preventive therapy should be made by a physician based on age, immune status, and underlying conditions. Excluding infection: In immunocompetent individuals, a negative result essentially rules out TB infection, avoiding unnecessary testing and anxiety. Our Solution for TB-IGRA Detection    

Hypertension: A Silent Killer Deserving your Concern Hypertension is one of the most common chronic diseases worldwide and a major risk factor for coronary heart disease, myocardial infarction, stroke, renal insufficiency, and even death. According to statistics, the annual number of deaths from cardiovascular diseases globally is approximately 19.2 million, and the number of deaths attributable to hypertension is about 10.8 million. Risk range     Hypertension can be primary (90–95%, unknown cause) or secondary (5–10%, due to conditions like renal artery stenosis, primary aldosteronism, or Cushing's syndrome). A blood pressure monitor tells you whether blood pressure is elevated, but it cannot answer why it is high or what damage has been caused. Priority groups for hypertension check-up 1. Young hypertensive patients (<40 years old). 2. Resistant hypertension (poorly controlled despite multiple medications). 3. Hypertension combined with abnormalities such as hypokalemia. 4. Patients with suspected secondary hypertension. 5. Hypertensive patients with coexistent obstructive sleep apnea. What are hypertension biomarkers Renin, Angiotensin I, Angiotensin II, ALD, ACTH and Cortisol are hypertension biomarkers using to assist in the differential diagnosis of primary and secondary hypertension by measuring hormone or factor levels, thereby providing a basis for clinical diagnosis and treatment. They are involved in the following pathways: Renin‑Angiotensin‑Aldosterone System (RAAS) The RAAS is a central hormonal cascade that regulates blood pressure, fluid balance, and systemic vascular resistance. When renal perfusion pressure drops or sodium delivery to the distal tubule decreases, the juxtaglomerular cells release renin. Renin converts angiotensinogen to angiotensin I, which is then converted by ACE to angiotensin II – a potent vasoconstrictor that also stimulates the adrenal cortex to secrete aldosterone. Aldosterone promotes sodium and water reabsorption in the kidneys, increasing blood volume and thereby raising blood pressure.     Hypothalamic‑Pituitary‑Adrenal (HPA) System The HPA axis is the body's central stress response system. CRH will stimulate the pituitary to release adrenocorticotropic hormone (ACTH). ACTH, in turn, acts on the adrenal cortex to secrete cortisol – a glucocorticoid that modulates metabolism, immune function, and vascular tone. Chronic cortisol excess leads to sodium and water retention, increased vascular reactivity to catecholamines, and ultimately sustained hypertension.     Our solution to fight against hypertension Getein offers hypertension testing on our advanced chemiluminescence platforms. These tests are not only easy to operate, but also provide highly accurate results, combining high sensitivity and excellent specificity.    

Getein Advanced Sandwich Assay Delivers Mass Spectrometry-level Accuracy for 25-OH-VD Test Results 25-OH-VD Testing Market Overview From 2024 to 2029, the global Vitamin D testing market is expected to experience accelerated growth. According to market research reports, the global Vitamin D testing market reached approximately USD 0.91 billion in 2023. By 2029, the global market size is projected to grow to around USD 1.57 billion. Key growth drivers include: Increasing public health awareness High prevalence of Vitamin D deficiency-related diseases Continuous growth of the aging population Prevalence of Vitamin D Deficiency Vitamin D deficiency has become a global public health concern, driven by modern lifestyles, reduced outdoor activity, and limited sun exposure. International clinical consensus and studies indicate that Vitamin D insufficiency is highly prevalent across diverse populations worldwide. Main causes include: Insufficient sunlight exposure Inadequate dietary intake Currently, there is no globally unified standard for assessing Vitamin D nutritional status. In China, the following classification is widely accepted: Serum 25-OH-VD Levels: <20 ng/mL (50 nmol/L): Deficiency 20–30 ng/mL (50–75 nmol/L): Insufficiency >30 ng/mL (>75 nmol/L): Sufficiency Multi-center studies in China show: Deficiency prevalence: 61.3% Insufficiency prevalence: up to 91.2% Clinical Value & Challenges Vitamin D testing is a fundamental assay in: Maternal and child health Bone metabolism management Chronic disease prevention However, clinical practice still faces three major challenges: Can domestic reagents match the accuracy of mass spectrometry (LC-MS/MS) and imported products? Are results consistent across different sample types (venous blood vs. capillary blood)? How to ensure both sensitivity and efficiency in routine testing? New Generation 25-OH-VD Assay by Getein Biotech Mass Spectrometry-Level Accuracy Reference method aligned with LC-MS/MS Traceable to NIST SRM 972 standard material Higher Sensitivity Dual-antibody sandwich design with enhanced signal amplification LOD as low as 1.0 ng/mL — no more missed low-value samples Wider Linear Range Expanded upper and lower detection limits Minimizes dilution and repeat testing Stronger Anti-Interference Capability Day-to-day precision CV <5% Stable performance across runs, ensuring reliable data and low retest rates Efficient & Convenient Results available in 8 minutes (POCT) Requires only 10-20 μL sample volume (S/P/WB/Peripheral Blood) Suitable for capillary blood and emergency/POCT scenarios Standardized Quality Assurance Continuously passes National Center for Clinical Laboratories (NCCL) external quality assessment programs Four Sample Types, One Calibration Curve Serum, plasma, whole blood, and capillary blood share a unified calibration system Clinical validation shows bias <5% Interchangeable sample types with consistent results and simplified workflow...

Getein's Automation: Precision Meets Speed—Transform Fecal Testing, Secure Gastrointestinal (GI)  Health!   Overview of Fecal Testing Fecal testing is a non-invasive, patient-friendly diagnostic tool for evaluating gastrointestinal (GI) health. It analyzes stool samples to detect hidden abnormalities, supporting routine screening, disease diagnosis, and treatment monitoring of GI disorders, with no need for invasive procedures like endoscopy. Currently, Getein’s test items include FOB, Calprotectin and H.pylori.     Current Challenges in Fecal Testing Manual operation: High human error risk and heavy workload. Low efficiency: Long turnaround times delaying clinical decisions. Contamination & safety risks: Direct sample contact increases cross-contamination and biohazard exposure. Inconsistent results: Lack of standardization across manual processes.   Getein 1200 & 1600: Automated Solutions     Full automation: Eliminates manual steps, reducing errors and ensuring consistency. High efficiency: Rapid processing handles high sample volumes, accelerating result delivery. Enhanced safety: Closed system minimizes contamination and staff exposure to biohazards. Standardized procedures: Ensures reliable, comparable results across batches/laboratories. User-friendly: Intuitive interface requires minimal training. High precision: Advanced technology ensures sensitive and specific detection.     Our Test Items Fecal Occult Blood Test (FOB) FOB is a cornerstone of colorectal cancer screening, as early-stage colorectal cancer often presents with occult bleeding. It also aids in diagnosing other GI conditions such as gastric ulcers, duodenal ulcers, inflammatory bowel disease (IBD), and vascular malformations. Timely FOB screening enables early detection of potentially life-threatening diseases, significantly reducing mortality rates through prompt treatment. Fecal Calprotectin Test Calprotectin testing is a gold standard for distinguishing inflammatory bowel disease (IBD, including Crohn’s disease and ulcerative colitis) from functional GI disorders (e.g., irritable bowel syndrome). It helps monitor disease activity, assess treatment response, and predict relapse in IBD patients. Additionally, it aids in evaluating inflammation in other conditions such as infectious colitis and celiac disease, guiding clinicians in formulating targeted treatment plans. Helicobacter pylori (Hp) Fecal Antigen Test Hp infection is strongly associated with chronic gastritis, peptic ulcers, gastric adenocarcinoma, and mucosa-associated lymphoid tissue (MALT) lymphoma. The fecal antigen test is a reliable method for diagnosing active Hp infection, especially in children and patients who cannot tolerate invasive tests (e.g., endoscopy) or urea breath tests. It also serves as an effective tool for post-treatment confirmation of Hp eradication, ensuring successful management of Hp-rel...