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Thyroid Function Diagnostics Solution
Admin | 22

December 2022

Thyroid disease is a global health problem that can substantially impact well-being, particularly in pregnancy and childhood. Statistics show that thyroid conditions are 5 to 10 times more common in women compared to men.

Hormones released by the thyroid gland play a crucial role in stimulating metabolism, growth, and calories processing.

 

Hypothalamus-Pituitary-Thyroid Axis

The hypothalamus-pituitary-thyroid (HPT) axis primarily functions to maintain normal circulating levels of thyroid hormones that are essential for the biological function of our tissues.

 

 

Signs and Symptoms of Thyroid Diseases

 

 

Features of Getein Thyroid Function Diagnostics Test Kits

 

  • Suitable for different types of analyzers
  • Simple operation, easy to use
  • Rapid: Get result in 15 minutes
  • Stable: Store at room temperature
  • Long shelf life: 24 months

 

Clinical Applications

 

Test Item Clinical Significance
TSH
  • The most sensitive biomarker for thyroid function
  • Diagnosis of subclinical thyroid dysfunction (subclinical hyperthyroidism and subclinical hypothyroidism)
  • Monitoring the efficacy of levothyroxine (L-T4) replacement therapy for primary hypothyroidism
  • Central hypothyroidism (pituitary and hypothalamic)
T3  T4
  • Direct indicators of thyroid function, but affected by TBG concentration
  • High levels of T3 and T4 often indicate an overactive thyroid, whereas low levels indicate an underactive thyroid
  • T3 is more sensitive to the diagnosis of mild hyperthyroidism, early hyperthyroidism and recurrence of hyperthyroidism after treatment
  • T4 decreases more obviously in hypothyroidism
fT3   fT4
  • Not affected by TBG concentration
  • Better indicators in the diagnosis of hyperthyroidism compared to T3 and T4
  • fT3 is a better indicator in monitoring the treatment efficacy of hyperthyroidism compared to fT4

 

Parameters

 

 


References

Ponto KA, Kahaly GJ. Autoimmune thyrotoxicosis: diagnostic challenges. The American Journal of Medicine.

Lechan RM, Hollenberg A, Fekete C. Hypothalamic-pituitary-thyroid axis: organization, neural/endocrine control of TRH. In: Squire LR, ed. Encyclopedia of Neuroscience. Oxford, UK: Academic Press; 2009:75-87.

Thyroid Function Tests. American Thyroid Association.

 

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