Thyroid disease is a global health problem that can substantially impact well-being, particularly in pregnancy and childhood. Statistics show that thyroid conditions are 5 to 10 times more common in women compared to men. Hormones released by the thyroid gland play a crucial role in stimulating metabolism, growth, and calories processing. Hypothalamus-Pituitary-Thyroid Axis The hypothalamus-pituitary-thyroid (HPT) axis primarily functions to maintain normal circulating levels of thyroid hormones that are essential for the biological function of our tissues. Signs and Symptoms of Thyroid Diseases Features of Getein Thyroid Function Diagnostics Test Kits Suitable for different types of analyzers Simple operation, easy to use Rapid: Get result in 15 minutes Stable: Store at room temperature Long shelf life: 24 months Clinical Applications Test Item Clinical Significance TSH The most sensitive biomarker for thyroid function Diagnosis of subclinical thyroid dysfunction (subclinical hyperthyroidism and subclinical hypothyroidism) Monitoring the efficacy of levothyroxine (L-T4) replacement therapy for primary hypothyroidism Central hypothyroidism (pituitary and hypothalamic) T3 T4 Direct indicators of thyroid function, but affected by TBG concentration High levels of T3 and T4 often indicate an overactive thyroid, whereas low levels indicate an underactive thyroid T3 is more sensitive to the diagnosis of mild hyperthyroidism, early hyperthyroidism and recurrence of hyperthyroidism after treatment T4 decreases more obviously in hypothyroidism fT3 fT4 Not affected by TBG concentration Better indicators in the diagnosis of hyperthyroidism compared to T3 and T4 fT3 is a better indicator in monitoring the treatment efficacy of hyperthyroidism compared to fT4 Parameters References Ponto KA, Kahaly GJ. Autoimmune thyrotoxicosis: diagnostic challenges. The American Journal of Medicine. Lechan RM, Hollenberg A, Fekete C. Hypothalamic-pituitary-thyroid axis: organization, neural/endocrine control of TRH. In: Squire LR, ed. Encyclopedia of Neuroscience. Oxford, UK: Academic Press; 2009:75-87. Thyroid Function Tests. American Thyroid Association.
Chronic kidney disease is a progressive condition that affects >10% of the general population worldwide, amounting to >800 million individuals. Chronic kidney disease has emerged as one of the leading causes of mortality worldwide, and it is one of a small number of non-communicable diseases that have shown an increase in associated deaths over the past 2 decades. Routine urinalysis and general kidney function tests can prompt early signs of Chronic kidney disease. Getein has developed and launched detection products related to renal function markers, which help to accelerate your Chronic kidney disease research! Getein Renal Function Test Solutions: mAlb NGAL CysC β2-MG
Control products refer to a substance, material, or article intended by its manufacturer to be used to verify the performance characteristics of an IVD medical device. Characteristics Stability Stable for 18 months at 2-8°C Interchangeability Using raw materials and diluent of human-matrix or human-like matrix, the quality control products are interchangeable with human samples. Traceability According to the requirements of lSO 17511:2003, Getein Biotech established the traceability of its testing system through the reference laboratory, so that the value of the quality control products can be traced to a higher-level reference material or reference method, thereby ensuring the accuracy of the quality control products assignment. Specifications 1 level x 6 vials x 1 mL 2 levels x 2 vials x 1 mL 3 levels x 2 vials x 1 mL 1 level x 3 vials x 1 mL 2 levels x 1 vial x 1 mL 3 levels x 1 vial x 1 mL Operation Procedure Applicable Devices >>Getein 1100<< >>Getein 1180<< >>Getein 1160<< >>Getein 1200<< >>Getein 1600<< Getein Quality Control Items