The severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) virus and resulting COVID‐19 pandemic present important diagnostic evaluation challenges. These range from understanding the value of signs and symptoms in predicting possible infection, assessing whether existing biochemical and imaging tests can identify infection and people needing critical care, and evaluating whether new diagnos...
What is cTnI? Troponin (Tn) is a complex of three regulatory proteins (C, I, T) that is integral to muscle contraction in skeletal muscle and cardiac muscle, but not smooth muscle. However, TnT and TnI in cardiac muscle are presented by forms different from those in skeletal muscles. Distribution of cTnI during AMI When AMI and myocardial cell damage occurs: The free cTnI in cardiac muscle is rele...
Getein PCT solution -- Sepsis diagnosis Sepsis, defined as a life-threatening organ dysfunction caused by a dysregulated host-response to infection, is a worldwide highly prevalent syndrome, associated with significant morbidity and mortality[1]. Important aspects of sepsis management are early diagnosis in the first few hours of triage[2]. However, the correct diagnosis and differentiation...
World Sepsis Day is a Global Sepsis Alliance initiative that started in 2012 and occurs every year on September 13th with events held all over the world to raise awareness about sepsis. World Sepsis Day is important because it is an opportunity for people worldwide to unite in the fight against sepsis which accounts for at least 8 million deaths worldwide annually [1]. Yet, depending on the...
As of November 20 of this year, a total of 52,807 laboratory-confirmed dengue cases and 230 associated deaths have been reported in Bangladesh this year, with a case fatality rate of 0.44%. Although dengue is a common endemic disease in Bangladesh, a surge in cases since June 2022 remains unusual. Several studies suggest that this year's high incidence of dengue cases is occurring aga...
Preface Influenza is a seasonal respiratory illness that occurs annually, usually peaking in winter. It affects 5-10% of adults and 20-30% of children each year.[1] This common, yet serious, infectious disease, represente a significant threat to public health. Globally, annual influenza epidemics are estimated to result in about 3 to 5 million cases of severe illness, millions of hospita...
Thyroid Problems & Disease: Types and Causes Prevalence of Thyroid Dysfunction Thyroid dysfunction is a common endocrine disorder worldwide. The prevalence varies across different populations and regions. 2 billion people or 30% of the world’s population are still at risk of iodine deficiency 20 million Americans are estimated to have some form of thyroid disease according to the ...
Things You May Want to Learn About Calprotectin Inflammatory bowel disease and the current diagnostic dilemma IBD are chronic diseases that result from the inflammation of the intestinal wall resulting in diarrhea, abdominal pain, fatigue, and weight loss. Crohn’s disease and ulcerative colitis are two major forms of IBD. [1.2] The diagnosis of IBD relies on a c...
