cTnI Fast Test Kit (Immunofluorescence Assay)

cTnI Fast Test Kit 

(Immunofluorescence Assay)

Intended Use

Cardiac Troponin I Fast Test Kit (Immunofluorescence Assay) is intended for in vitro quantitative determination of Cardiac Troponin I (cTnI) in human serum, plasma or whole blood samples. This test is used as an aid in the diagnosis of myocardial injury such as Acute Myocardial Infarction (AMI), Unstable Angina, Acute Myocarditis and Acute Coronary Syndrome (ACS).

About cTnI

Troponin, a molecular complex that is bound to the thin filament (actin) of striated muscle fibers, acts with intracellular calcium to control the interaction of the thin filament with the thick filament (myosin), thus regulating muscle contraction.

Troponin consists of three regulatory proteins: T, which connects the troponin complex and tropomyosin (another cardiac muscle regulatory protein); I, which prevents muscle contraction in the absence of calcium; C, which binds calcium. Cardiac Troponin I (MW 22.5 kDa) and the two skeletal muscle isoforms of Troponin I have considerable amino acid sequence homology, but cTnI contains an additional N-terminal sequence and is highly specific for myocardium.

Due to the high myocardial specificity and the long duration of elevation, cTnI has become an important marker in the diagnosis and evaluation of patients suspected of having an acute myocardial infarction (AMI).

Specifications

Applicable Device

Getein 1100 Immunofluorescence Quantitative Analyzer

Getein 1150 Immunofluorescence Quantitative Analyzer

Getein 1160 Immunofluorescence Quantitative Analyzer

Getein 1180 Immunofluorescence Quantitative Analyzer

Getein 1600 Immunofluorescence Quantitative Analyzer

Getein 1200 Immunofluorescence Quantitative Analyzer

Getein 208 Hand-held Integrated System